Sasuke was sent to investigate coordinates discovered in intel recovered by Konohamaru, a location accessible only through space–time ninjutsu. Orochimaru denies responsibility, confessing that Shin is an old experiment he has long before lost control of, and says that Shin's "sons" are actually his genetic clones.

Deciding the best course was to capture Naruto, Urashiki subdued Naruto and trap Boruto and Sasuke, along with Jiraiya, who happened along inside a stone prison.

Sasuke is paired against For the final matches taking place in a month, Sasuke was to face Sasuke is saved by the timely arrival of Naruto and Sakura, sent by Kakashi to provide assistance. As he leaves the village, he is met by Naruto, who returns to him his Sasuke returns to Konoha after destroying a meteorite.Two years after the war, Sasuke crosses paths with Sasuke finds the group attacking the village and defeats them, saving all the villagers from harm.

Having finally accepted that Itachi was a good person who was wronged by Konoha, he decides that the new mission for their team, now renamed "Taka", will be to destroy Konoha. When his Rinnegan recharges from his earlier dimensional travels, Sasuke manifests his Susanoo and transports Naruto, Sarada, and Chōchō to Shin's hideout. Once they're far enough away from Konoha, the Sound Four give Sasuke some medication that will mature his cursed seal to a second, stronger stage. Ultimately however, Sasuke decided that letting himself be used by Orochimaru would be a disgrace to his clan, turning on Orochimaru and acquires new After Itachi dies in battle with Sasuke and he learned that the hateful older brother that Itachi seemed to be was all an act and that, in truth, Sasuke was the most precious person to Itachi; his murder of the Uchiha was done on the instructions of During his time as a wanderer, Sasuke was a recluse, keeping contact with people to an absolute minimum and maintained his strong sense of pride; he is willing to help the villages if their problems are beyond their expertise but ignores their requests if facing insignificant issues. Sasuke was a happy child, eager to please and be worthy of his clan name.In his pursuit for the power to take his revenge, whenever he meets new people, he makes an evaluation of their abilities: those he perceives to be weaker than himself he arrogantly disregards, giving them little attention so that they won't hold him back; those he perceives as stronger he fixates over and tries to surpass. Sasuke later meets with Orochimaru and his former team Taka comrades to investigate the matter further.

Sasuke was forced to spent time to recover his chakra to return to Sunagakure, as his Rinnegan was too weak to maintain a portal. Naruto and Sasuke continued to engage Jigen, eventually pushing him into a corner, at which point Jigen responded by progressing his Kāma to the next stage, worrying Sasuke who saw it first-hand. When this doesn't work, Sakura confesses her love for him and asks to be allowed to accompany him at the very least. Just as he was about to leave Naruto stranded, Sasuke, having detected Naruto's chakra and followed him there, appeared and kicked Jigen away to stop him from leaving before proceeding to team up with Naruto to fight Jigen, free to fight at full power, but even then Jigen successfully pressured them with his ability to seemingly conjure black rods from nowhere to stab them.

Jiraiya could tell that Sasuke and Boruto's desire to protect Naruto was genuine and that they had their reasons for keeping secrets, he made a deal with Sasuke not to delve deeper into their true identities provided that Sasuke reveal all he knows about Urashiki. Stemming from his inspiration of Itachi protecting the Land of Fire from the shadows, he also sometimes acts independently on his own and helps the five nations, but does not even bother to interact with anyone during such instances if not needed. He discovered an Ōtsutsuki related site, which contained records on some of their members, specifically those who had been to their world, which also led him to believe Kaguya came to this world with a partner. Sasuke tells Sarada to not make such a face and pokes her on the forehead, promising to come home soon, which makes her very happy and prompts her to smile at Sakura. Before they could formulate a proper plan, Sasuke detected Urashiki's return, speeding off with Jiraiya to help Boruto and Naruto. Sasuke tells Boruto to ask him again after he's learned to use the After his day training with Sasuke, the two sit by a fire and talk. Ashamed of his past actions, Sasuke referred to the person he used to be as an entirely different person when he told Boruto about his past actions, albeit without directly telling Boruto he was referring to himself.