Häufig sind sich daher angehende Mediziner, Gastronomen, Krankenpfleger, Pädagogen unsicher, ob sie durch ihre Erkrankung einer erhöhte Gefahr für ihre Umgebung darstellen. Lau GK, Increases in acute hepatitis B virus infections—Kentucky, Tennessee, and West Virginia, 2006-2013. et al. et al. Recommendations of the Advisory Committee on Immunization Practices for use of a hepatitis B vaccine with a novel adjuvant. The vaccine and HBIG will greatly reduce the chance of your baby getting the infection.If you have hepatitis B, you should eat a balanced, healthy diet. Pharmacological interventions for acute hepatitis B infection: an attempted network meta-analysis.

Treatment should be individualized based on clinical and laboratory characteristics and the risks of developing cirrhosis and hepatocellular carcinoma.

Lok AS,

Centers for Disease Control and Prevention.
Hepatitis B vaccination is recommended for medically stable infants weighing 2,000 g or more within 24 hours of birth, unvaccinated infants and children, and unvaccinated adults requesting protection from hepatitis B or who are at increased risk of infection. Centers for Disease Control and Prevention, Division of Nutrition, Physical Activity, and Obesity website. Williams I, European Association for the Study of the Liver. Copyright © 2019 by the American Academy of Family Physicians.This page will be removed from your Favorites Links. Vellozzi C, Chan HL, Your doctor may recommend additional tests to find out whether you have liver damage, how much liver damage you have, or to rule out other causes of liver disease. This can also protect babies from getting the infection from mothers with hepatitis B infection. American Association for the Study of Liver Diseases.

Viral hepatitis surveillance. Abara WE, Carrilho FJ, THAD WILKINS, MD, MBA; RICHARD SAMS, MD, MA; and MARY CARPENTER, PharmD Medical College of Georgia at Augusta University, Augusta, GeorgiaHepatitis B virus (HBV) is a partly double-stranded DNA virus that causes acute and chronic liver infection. Acute hepatitis B is defined as the discrete onset of symptoms, the presence of jaundice or elevated serum alanine transaminase levels, and test results showing hepatitis B surface antigen and hepatitis B core antigen. All three test results are needed to fully understand whether a person is infected or not.

Heimbach JK, ; Misra SP, This figure may not include all potential targets of drugs under development. Hwang JP, Entecavir doses in treatment-experienced children older than two years and at least 10 kg are: 0.3 mg (10 to 11 kg), 0.4 mg (> 11 to 14 kg), 0.5 mg (> 14 to 17 kg), 0.6 mg (> 17 to 20 kg), 0.7 mg (> 20 to 23 kg), 0.8 mg (> 23 to 26 kg), 0.9 mg (> 26 to 30 kg), and 1 mg (> 30 kg).Pegylated interferon alfa-2a (Pegasys), interferon alfa-2b (Intron A) May cause or exacerbate autoimmune, infectious, ischemic, thyroid, and neuropsychiatric disorders, and hemorrhagic cerebrovascular events Adults: Flulike symptoms, bone marrow suppression, headache, fatigue Pegylated interferon alfa-2a had 30% HBeAg seroconversion and HBV DNA suppression compared with placebo Oral antiviral agents (nucleoside/nucleotide analogues) Use caution in patients with renal impairment or individuals at risk of renal toxicity, including concurrent nephrotoxic agents or nonsteroidal anti-inflammatory drug use Acute renal failure, Fanconi syndrome, nephrogenic diabetes insipidus, lactic acidosis/hepatomegalyPancreatitis, lactic acidosis/hepatomegaly, immune reconstitution syndrome, headache, fatigue, fat redistribution Telbivudine (no longer available in the United States) Use caution in individuals who did not respond to previous lamivudine therapy and in those with renal impairment Myopathy, peripheral neuropathy, lactic acidosis/hepatomegalyNephropathy, Fanconi syndrome, osteomalacia, lactic acidosis/hepatomegalyALT = alanine transaminase; anti-HBe = antibodies to hepatitis B e antigen; HBeAg = hepatitis B e antigen; HBsAg = hepatitis B surface antigen; HBV = hepatitis B virus. Ward JW.

Your doctor will use regular blood tests to check for signs of liver damage, find out if you need treatment, or see how you are responding to treatment.Blood tests can also show whether you are immune to hepatitis B, meaning you can’t get hepatitis B. McMahon BJ, In acute infection, some may develop a rapid onset of sickness with vomiting, yellowish skin, tiredness, dark urine and abdominal pain. A systematic review and meta-analysis of management options for adults who respond poorly to hepatitis B vaccination. Hepatitis B ist weltweit verbreitet.

Zhang YG, The presence of anti-HBc may also indicate chronic hepatitis B or a false-positive result.‡—The presence of anti-HBs indicates recovery and immunity from hepatitis B or successful immunization against HBV.The Advisory Committee on Immunization Practices recommends hepatitis B vaccination for all medically stable infants weighing 2,000 g (4 lb, 6 oz) or more within 24 hours of birth, unvaccinated infants and children, and unvaccinated adults requesting protection from hepatitis B or who are at increased risk of infection.Postvaccination testing is recommended only in individuals who may not elicit a complete response to the vaccine based on risk factor assessment. The average hepatitis B incubation period is 120 days, but it can range from 45 to 160 days.

Lok ASF, Heathcote EJ,

; Natural history of acute and chronic hepatitis B: The role of HBV genotypes and mutants. In Deutschland haben ca. 7% der Bevölkerung die Erkrankung durchgemacht, ca. Loglio A, March 2015.

These tests may includeDoctors typically use liver biopsy only if other tests don’t provide enough information about a person’s liver damage or disease. Treatment of hepatitis B: Is there still a role for interferon? A meta-analysis including 14 studies involving 2,829 individuals found improved treatment effectiveness with combined therapy (peginterferon alfa-2a and nucleoside/nucleotide analogue); however, because of heterogeneity among trials and lack of consistent evidence, current guidelines recommend monotherapy.The primary drawback of peginterferon alfa-2a is tolerability because this therapy is associated with frequent adverse effects (i.e., flulike symptoms, fatigue, mood disturbances, cytopenias, autoimmune disorders in adults, and anorexia and weight loss in children).The 2018 guidelines from the American Association for the Study of Liver Diseases recommend tenofovir alafenamide for initial therapy in adults with immune-active chronic hepatitis B. Tenofovir alafenamide should also be considered in patients with or at risk of renal dysfunction or bone disease.